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What is Sculptra® Aesthetic?
Sculptra Aesthetic is an FDA-approved injectable that helps gradually replace lost collagen—the most common protein in the body that is used to form a framework to support cell and tissue—for results that can last more than two years.*
SCULPTRA AESTHETIC WORKS WITH YOUR BODY TO HELP REBUILD LOST COLLAGEN
Why Sculptra Aesthetic?
Not all anti-aging treatments are the same:
Collagen Creams: Collagen Creams do not fully penetrate the dermis, so most topical treatments are effective as moisturizers that briefly improve the skin’s appearance.1-3
Collagen Supplements: When ingested, the digestive system breaks down collagen proteins and their effectiveness remains inconclusive.4,5
Toxins: Toxins temporarily weaken muscles to minimize frown lines in the forehead. Results typically last a couple of months.6,7
Fillers: Works immediately upon injection to fill in lines, wrinkles and folds.8
SCULPTRA AESTHETIC ADDRESSES AN UNDERLYING CAUSE OF FACIAL AGING, NOT JUST THE SYMPTOMS
As a poly-L-lactic acid (PLLA) collagen stimulator, Sculptra Aesthetic helps restore the deep, underlying structure of the skin to diminish facial wrinkles.
Sculptra Aesthetic works with your body within the deep dermis to help revitalize collagen production and help restore your skin’s inner structure and volume.9-11
As the Sculptra Aesthetic PLLA microparticles are absorbed, they help stimulate collagen production.9-11
Rebuilt collagen strands begin gradually helping to restore facial volume and the look of fullness to wrinkles and folds.12
How does Sculptra Aesthetic work?
Sculptra Aesthetic is made with biocompatible, biodegradable, synthetic material called poly-L-lactic acid, which is gradually and naturally absorbed by the body and helps to rebuild lost collagen through a series of treatments administered by a trained specialist.
The specialist injects treatment within the deep dermis, where strands of collagen support your skin’s structure. Over time, Sculptra Aesthetic helps the body reproduce lost collagen.9-11 The number of injection appointments and the number of injections per appointment vary from person to person, depending on how much collagen has been lost. On average, three injection appointments are needed over a period of a few months.
Significant Difference, Long-Lasting Results
*Individual results and treatment regimens may vary. Clinical trial ended at 25 months.
Sculptra® Aesthetic works gradually. Explore real patients’ significant, subtle results, treatment-by-treatment.†
†Individual results and treatment regimens may vary.
Treated with 3 vials of Sculptra Aesthetic.
Frequently Asked Questions
- Is Sculptra Aesthetic FDA approved?
Yes. The F.D.A. has approved Sculptra Aesthetic for the correction of shallow to deep nasolabial fold (smile lines) contour deficiencies and other facial wrinkles which are treated with the appropiate injection technique in healthy people.
- What is Sculptra Aesthetic?
Sculptra Aesthetic is a facial injectable that helps gradually replace lost collagen and correct shallow–to-deep nasolabial folds, also known as smile lines. The main ingredient in Sculptra Aesthetic is poly-L-lactic acid or PLLA.
- How many visits or injections will I need?
The number of treatment sessions, the length of treatment, and the amount of Sculptra Aesthetic differs for each person. Your Sculptra Aesthetic trained Physician will create a regimen that works for unique needs of your face. Sculptra Aesthetic works over time, for most patients, and average of 3 treatments session over a few months.
- When will I start seeing improvements from Sculptra Aesthetic?
Sculptra Aesthetic gives you gradual results that can last up to 2 years. In a study, 100% of patients showed improvement in wrinkles and lines at 3 weeks.
*individual results and treatment sessions may vary.
- What are the possible side effects?
The most common side effects with the use of Sculptra Aesthetic include injection related side effects at the site of the injection, such as bleeding, tenderness or pain, redness bruising or swelling.
You should not use Sculptra Aesthetic if you are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring.
Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC. Skin anti-aging strategies. Dermatoendocrinol. 2012;4(3):308–319.
Zhang S, Duan E. Fighting against Skin Aging: The Way from Bench to Bedside. Cell Transplant. 2018;27(5):729–738.
Wrinkle creams: Your guide to younger looking skin. Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/wrinkles/in-depth/wrinkle-creams/art-20047463. Accessed January 17, 2020.
Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7.
Can collagen supplements help tighten loose skin? Cleveland Clinic website. https://health.clevelandclinic.org/can-collagen-supplements-help-tighten-loose-skin/. Accessed January 17, 2020.
Botox injections. Mayo Clinic website. https://www.mayoclinic.org/tests-procedures/botox/about/pac-20384658. Accessed January 17, 2020.
Wrinkles. Mayo Clinic website. https://www.mayoclinic.org/diseases-conditions/wrinkles/diagnosis-treatment/drc-20354931. Accessed December 3, 2019.
Injectable fillers guide. American Board of Cosmetic Surgery website. https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/injectable-fillers-guide/. Accessed January 17, 2020.
Stein P, Vitavska O, Kind P, Hoppe W, Wieczorek H, Süchurer NY. The biological basis for poly-L-lactic acid-induced augmentation. J Dermatol Sci. 2015;78(1):26–33.
Goldberg D, Guana A, Volk A, Daro-Kaftan E. Single-arm study for the characterization of human tissue response to injectable poly-L-lactic acid. Dermatol Surg. 2013;39(6):915–922.
Sculptra Aesthetic injectable poly-L-lactic acid. Instructions for Use. Galderma Laboratories. 2016.
Gogolewski S, Jovanovic M, Perren SM, Dillon JG, Hughes MK. Tissue response and in vivo degradation of selected polyhydroxyacids: polylactides (PLA), poly(3-hydroxybutyrate) (PHB), and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB/VA). J Biomed Mater Res. 1993;27(9):1135–1148.
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Important Safety Information
Indication: Sculptra® Aesthetic (injectable poly-L-lactic acid) is indicated for use in people with healthy immune systems as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate.
Sculptra Aesthetic should not be used by people that are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring. Safety has not been established in patients who are pregnant, lactating, breastfeeding, or under 18 years of age.
Sculptra Aesthetic has unique injection requirements and should only be used by a trained healthcare practitioner. Contour deficiencies should not be overcorrected because they are expected to gradually improve after treatment.
Sculptra Aesthetic should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Use at the site of skin sores, cysts, pimples, rashes, hives or infection should be postponed until healing is complete. Sculptra Aesthetic should not be injected into the red area (vermillion) of the lip or in the peri-orbital area.
The most common side effects after initial treatment include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. Other side effects may include small lumps under the skin that are sometimes noticeable when pressing on the treated area. Larger lumps, some with delayed onset with or without inflammation or skin discoloration, have also been reported.
Sculptra Aesthetic is available only through a licensed practitioner.